User:Mr. Ibrahem/Lipid emulsion
Clinical data | |
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Trade names | Intralipid, Nutrilipid, others |
Other names | Fat emulsion, lipid emulsion therapy, lipid resuscitation therapy |
AHFS/Drugs.com | FDA Professional Drug Information |
Lipid emulsion, sold under the brand name Intralipid among others, is a oil based solution for intravenous use.[2] They are traditionally used as part of parenteral nutrition.[2] They are also used to treat a number of toxicities including local anesthetic, beta-blocker, calcium channel blocker, organophosphate, and antipsychotic.[1][2]
Side effects are generally few, though may include allergies, pancreatitis and adult respiratory distress syndrome.[1] Use may be complicated by certain fungal infections.[2] How it works in toxicity is not entirely clear.[1]
Lipid emulsions became available for medical use in 1961.[2] It use for toxicity began in 1998.[3] Different versions are made from different source.[1] Common sources include soy bean, coconut, olive, eggs, and fish.[1] In the United States it costs about 47 USD per 250 ml of 20% emulsion as of 2021.[4]
References[edit]
- ^ a b c d e f g Sepulveda, EA; Pak, A (January 2021). "Lipid Emulsion Therapy". PMID 31751087.
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(help) - ^ a b c d e f Spray, JW (2016). "Review of Intravenous Lipid Emulsion Therapy". Journal of infusion nursing : the official publication of the Infusion Nurses Society. 39 (6): 377–380. doi:10.1097/NAN.0000000000000194. PMID 27828934.
- ^ Fettiplace, MR; Weinberg, G (September 2015). "Past, Present, and Future of Lipid Resuscitation Therapy". JPEN. Journal of parenteral and enteral nutrition. 39 (1 Suppl): 72S–83S. doi:10.1177/0148607115595979. PMID 26187938.
- ^ "Intralipid Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 26 May 2021. Retrieved 14 April 2021.