AKR7A3

AKR7A3
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2CLP
Identifiers
Aliases	AKR7A3, AFAR2, aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase), aldo-keto reductase family 7 member A3
External IDs	OMIM: 608477 HomoloGene: 49295 GeneCards: AKR7A3
Gene location (Human) Chr. Chromosome 1 (human) Band 1p36.13 Start 19,282,573 bp End 19,288,770 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in duodenum jejunal mucosa body of pancreas right lobe of liver pancreatic ductal cell kidney cardia body of stomach gallbladder pylorus n/a More reference expression data BioGPS n/a
Gene ontology Molecular function electron transfer activity oxidoreductase activity aldo-keto reductase (NADP) activity protein binding identical protein binding alditol:NADP+ 1-oxidoreductase activity Cellular component cytoplasm extracellular exosome cytosol Biological process xenobiotic metabolic process cellular aldehyde metabolic process electron transport chain aflatoxin metabolic process aflatoxin catabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22977 n/a Ensembl ENSG00000162482 n/a UniProt O95154 n/a RefSeq (mRNA) NM_012067 n/a RefSeq (protein) NP_036199 n/a Location (UCSC) Chr 1: 19.28 – 19.29 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Aldo-keto reductase family 7 member A3 is a protein that in humans is encoded by the AKR7A3 gene.

Function

Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004].

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Aflatoxin B1 aldehyde reductase member 3 (AKR7A3)

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.