User:Mr. Ibrahem/Tioconazole
 | |
| Clinical data | |
|---|---|
| Trade names | Vagistat-1, others |
| Other names | Thioconazole |
| AHFS/Drugs.com | Monograph |
| Routes of administration | Topical |
| Drug class | Imidazole[1] |
| Legal status | |
| Legal status |
|
| Identifiers | |
| |
| Chemical and physical data | |
| Formula | C16H13Cl3N2OS |
| Molar mass | 387.70 g·mol−1 |
| Chirality | Racemic mixture |
  (what is this?) (verify) | |
Tioconazole, sold under the brand names Vagistat among others, is an antifungal medication used to treat vaginal yeast infections and fungal nail infections.[1][2] It is applied to the site of infection.[1][2] For nails, it may be used for 6 to 12 months.[2]
Common side effects include burning, itching, and headache.[1] It is in the imidazole class and believed to work by affected the fungal cellular membrane.[1]
Tioconazole was patented in 1975 and approved for medical use in 1982.[3] It is available as a generic medication and over the counter.[2][1] In the United Kingdom a bottle of the medication for us on the nails costs the NHS about £28 as of 2021.[2] In the United States a single dose for in the vagina costs about 10 USD.[4]
References[edit]
- ^ a b c d e f g h "Tioconazole Monograph for Professionals". Drugs.com. Archived from the original on 5 August 2019. Retrieved 4 October 2021.
- ^ a b c d e f BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 1299. ISBN 978-0-85711-369-6.
{{cite book}}: CS1 maint: date format (link) - ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 503. ISBN 9783527607495. Archived from the original on 2017-09-10. Retrieved 2021-01-25.
- ^ "Compare Tioconazole Prices - GoodRx". GoodRx. Retrieved 4 October 2021.