User:Mr. Ibrahem/Teriparatide
Clinical data | |
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Trade names | Forteo, Forsteo, Teribone, Bonsity |
AHFS/Drugs.com | Monograph |
MedlinePlus | a603018 |
License data |
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Pregnancy category |
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Routes of administration | Subcutaneous |
Drug class | Parathyroid hormone (PTH) |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Bioavailability | 95% |
Metabolism | Liver (nonspecific proteolysis) |
Elimination half-life | Subcutaneous: 1 hour |
Excretion | Kidney (metabolites) |
Chemical and physical data | |
Formula | C181H291N55O51S2 |
Molar mass | 4117.77 g·mol−1 |
3D model (JSmol) | |
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Teriparatide, sold under the brand name Forteo among others, is a form of parathyroid hormone (PTH) used to treat osteoporosis.[2] It may be used in those in who bisphosphonates do not work or those at very high risk.[2] It is given by injection under the skin.[2] It may be used for up to two years.[3]
Common side effects include pain, nausea, rash, depression, and problems with the teeth.[2] Other side effect may include an increased risk of osteosarcoma, anaphylaxis, low blood pressure with standing.[2] It consists of the active portion of PTH and works by promoting bone formation.[2][4]
Teriparatide was approved for medical use in the United States in 2002 and Europe in 2003.[2][4] In the United Kingdom a month supply costs the NHS about £240 as of 2021.[3] This amount in the United States costs about 3,900 USD.[5]
References[edit]
- ^ a b "Teriparatide Use During Pregnancy". Drugs.com. 25 November 2019. Archived from the original on 27 October 2020. Retrieved 14 September 2020.
- ^ a b c d e f g h i "Teriparatide". drugs.com. American Society of Health-System Pharmacists. Archived from the original on 29 June 2021. Retrieved 1 October 2021.
- ^ a b c BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 774. ISBN 978-0-85711-369-6.
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: CS1 maint: date format (link) - ^ a b "Forsteo EPAR". European Medicines Agency (EMA). 17 September 2018. Archived from the original on 27 June 2020. Retrieved 26 June 2020.
- ^ "Forteo". Goodrx.com. Archived from the original on 11 November 2016. Retrieved 1 October 2021.