User:Mr. Ibrahem/Pentosan polysulfate
 | |
| Clinical data | |
|---|---|
| Other names | Pentosan polysulfate sodium, (1->4)-β-Xylan 2,3-bis(hydrogen sulfate) with a 4 O-methyl-α-D-glucuronate |
| AHFS/Drugs.com | Monograph |
| Pregnancy category |
|
| Routes of administration | By mouth |
| Drug class | Heparinoid[1] |
| Pharmacokinetic data | |
| Excretion | Urine |
| Chemical and physical data | |
| Formula | (C5H6Na2O10S2)n |
| (verify) | |
Pentosan polysulfate (PPS), sold under the brand name Elmiron among others, is a medication used for bladder pain syndrome.[1] It is taken by mouth.[1]
Common side effects include hair loss, diarrhea, nausea, blood in the stool, rash, liver problems, and abdominal pain.[1] Other side effects may include eye problems and infection.[2] It is a partly manufactured heparinoid.[1] It is believed to work by attaching to the bladder wall protecting it.[3]
Pentosan polysulfate was approved for medical use in the United States in 1996 and Europe in 2017.[1] In the United States it costs about 900 USD per month as of 2021.[3] In the United Kingdom this amount costs the NHS about £450.[2]
References[edit]
- ^ a b c d e f g h i "Pentosan Monograph for Professionals". Drugs.com. Archived from the original on 23 January 2021. Retrieved 27 October 2021.
- ^ a b BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 835. ISBN 978-0857114105.
- ^ a b "Elmiron Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 6 August 2020. Retrieved 27 October 2021.