User:Mr. Ibrahem/Galcanezumab
 | |
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Humanized |
| Target | CALCA, CALCB |
| Clinical data | |
| Trade names | Emgality |
| Other names | LY2951742, galcanezumab-gnlm |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a618063 |
| License data |
|
| Routes of administration | Subcutaneous injection |
| Drug class | CGRP antagonist[1] |
| Legal status | |
| Legal status |
|
| Chemical and physical data | |
| Formula | C6392H9854N1686O2018S46 |
| Molar mass | 144083.69 g·mol−1 |
Galcanezumab, sold under the brand name Emgality, is a medication used to prevent migraines and treat cluster headaches.[1] It is given by injection under the skin.[1] Benefits may take up to three months.[1]
Common side effects include pain or redness at the site of injection.[2] Other side effects may include allergic reactions.[1] Safety in pregnancy is unclear.[1] It is a monoclonal antibody that attaches to and blocks calcitonin gene-related peptide (CGRP), thereby helping blood vessels to return to their normal size.[2]
Galcanezumab was approved for medical use in the United States and Europe in 2018.[4][2] In the United Kingdom it costs the NHS about £450 per month as of 2021.[3] This amount in the United States is about 580 USD.[5]
References[edit]
- ^ a b c d e f g "Galcanezumab-gnlm Monograph for Professionals". Drugs.com. Archived from the original on 7 December 2019. Retrieved 2 December 2021.
- ^ a b c d "Emgality EPAR". European Medicines Agency (EMA). Archived from the original on 22 May 2020. Retrieved 28 April 2020.
This article incorporates text from this source, which is in the public domain.
- ^ a b BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 499. ISBN 978-0857114105.
- ^ "Drug Trials Snapshots: Emgality". U.S. Food and Drug Administration (FDA). 23 October 2018. Archived from the original on 7 December 2019. Retrieved 7 December 2019. This article incorporates text from this source, which is in the public domain.
- ^ "Emgality Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 20 October 2021. Retrieved 2 December 2021.
