User:Mr. Ibrahem/Chlamydia

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Chlamydia
Other namesChlamydia infection
Pap smear showing C. trachomatis (H&E stain)
Pronunciation
SpecialtyInfectious disease, gynecology, urology
SymptomsNone, vaginal discharge, discharge from the penis, burning with urination[1]
ComplicationsPain in the testicles, pelvic inflammatory disease, infertility, ectopic pregnancy[1][2]
Usual onsetFew weeks following exposure[1]
CausesChlamydia trachomatis spread by sexual intercourse or childbirth[3]
Diagnostic methodUrine or swab of the cervix, vagina, or urethra[2]
PreventionNot having sex, condoms, sex with only one non–infected person[1]
TreatmentAntibiotics (azithromycin or doxycycline)[2]
Frequency4.2% (women), 2.7% (men)[4][5]
Deaths~200 (2015)[6]

Chlamydia, or more specifically a chlamydia infection, is a sexually transmitted infection caused by the bacterium Chlamydia trachomatis.[3] Most people who are infected have no symptoms.[1] When symptoms do appear it can be several weeks after infection.[1] Symptoms in women may include vaginal discharge or burning with urination.[1] Symptoms in men may include discharge from the penis, burning with urination, or pain and swelling of one or both testicles.[1] The infection can spread to the upper genital tract in women, causing pelvic inflammatory disease, which may result in future infertility or ectopic pregnancy.[2] Repeated infections of the eyes that go without treatment can result in trachoma, a common cause of blindness in the developing world.[7]

Chlamydia can be spread during vaginal, anal, or oral sex, and can be passed from an infected mother to her baby during childbirth.[1] The eye infections may also be spread by personal contact, flies, and contaminated towels in areas with poor sanitation.[7] Chlamydia trachomatis only occurs in humans.[8] Diagnosis is often by screening which is recommended yearly in sexually active women under the age of twenty-five, others at higher risk, and at the first prenatal visit.[1][2] Testing can be done on the urine or a swab of the cervix, vagina, or urethra.[2] Rectal or mouth swabs are required to diagnose infections in those areas.[2]

Prevention is by not having sex, the use of condoms, or having sex with only one other person, who is not infected.[1] Chlamydia can be cured by antibiotics with typically either azithromycin or doxycycline being used.[2] Erythromycin or azithromycin is recommended in babies and during pregnancy.[2] Sexual partners should also be treated and the infected people advised not to have sex for seven days and until symptom free.[2] Gonorrhea, syphilis, and HIV should be tested for in those who have been infected.[2] Following treatment people should be tested again after three months.[2]

Chlamydia is one of the most common sexually transmitted infections, affecting about 4.2% of women and 2.7% of men worldwide.[4][5] In 2015 about 61 million new cases occurred globally.[9] In the United States about 1.4 million cases were reported in 2014.[3] Infections are most common among those between the ages of 15 and 25 and are more common in women than men.[2][3] In 2015 infections resulted in about 200 deaths.[6] The word chlamydia is from the Greek χλαμύδα, meaning "cloak".[10][11]

References[edit]

  1. ^ a b c d e f g h i j k "Chlamydia – CDC Fact Sheet". CDC. May 19, 2016. Archived from the original on 11 June 2016. Retrieved 10 June 2016.
  2. ^ a b c d e f g h i j k l m "2015 Sexually Transmitted Diseases Treatment Guidelines". CDC. June 4, 2015. Archived from the original on 11 June 2016. Retrieved 10 June 2016.
  3. ^ a b c d "2014 Sexually Transmitted Diseases Surveillance Chlamydia". November 17, 2015. Archived from the original on 10 June 2016. Retrieved 10 June 2016.
  4. ^ a b Newman, Lori; Rowley, Jane; Vander Hoorn, Stephen; Wijesooriya, Nalinka Saman; Unemo, Magnus; Low, Nicola; Stevens, Gretchen; Gottlieb, Sami; Kiarie, James; Temmerman, Marleen; Meng, Zhefeng (8 December 2015). "Global Estimates of the Prevalence and Incidence of Four Curable Sexually Transmitted Infections in 2012 Based on Systematic Review and Global Reporting". PLOS ONE. 10 (12): e0143304. Bibcode:2015PLoSO..1043304N. doi:10.1371/journal.pone.0143304. PMC 4672879. PMID 26646541.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  5. ^ a b "Sexually transmitted infections (STIs) Fact sheet N°110". who.int. December 2015. Archived from the original on 25 November 2014. Retrieved 10 June 2016.
  6. ^ a b GBD 2015 Mortality and Causes of Death, Collaborators. (8 October 2016). "Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1459–1544. doi:10.1016/s0140-6736(16)31012-1. PMC 5388903. PMID 27733281. {{cite journal}}: |first1= has generic name (help)CS1 maint: numeric names: authors list (link)
  7. ^ a b "CDC – Trachoma, Hygiene-related Diseases, Healthy Water". Centers for Disease Control and Prevention. December 28, 2009. Archived from the original on September 5, 2015. Retrieved 2015-07-24.
  8. ^ Graeter, Linda (2014). Elsevier's Medical Laboratory Science Examination Review. Elsevier Health Sciences. p. 30. ISBN 9780323292412. Archived from the original on 2017-09-10.
  9. ^ GBD 2015 Disease and Injury Incidence and Prevalence, Collaborators. (8 October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282. {{cite journal}}: |first1= has generic name (help)CS1 maint: numeric names: authors list (link)
  10. ^ Stevenson, Angus (2010). Oxford dictionary of English (3rd ed.). New York, NY: Oxford University Press. p. 306. ISBN 9780199571123. Archived from the original on 10 September 2017. Retrieved 10 June 2016.
  11. ^ Byrne, Gerald I. (8 July 2003). "uncloaked". Proceedings of the National Academy of Sciences. 100 (14): 8040–8042. doi:10.1073/pnas.1533181100. PMC 166176. PMID 12835422. The term was coined based on the incorrect conclusion that Chlamydia are intracellular protozoan pathogens that appear to cloak the nucleus of infected cells.