Talk:Pharmacology of antidepressants

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Pharmacology High‑importance

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Trazodone 367 >10000 >10000 220 >35000 42 320 118 35.8 224 4142 ? ?

Trazodone affinities for sigma receptors seem wrong (or right), if u go to the page https://en.wikipedia.org/wiki/Trazodone the affinities are different Not only are the affinities for Trazodone (as mentioned above) different, but they are also different for Fluoxetine. The page dedicated to Fluoxetine lists affinities (Ki) which are significantly different than of those listed on this page. I am guessing this is true for alot of the drugs. — Preceding unsigned comment added by 73.110.0.19 (talk) 14:30, 9 May 2017 (UTC)[reply]

determination of affinities is very error-prone, so there often are multiple values for one and the same drug, depending on the source. It's often wiser to give a span instead of an exact value.

--78.54.150.69 (talk) 17:54, 15 July 2017 (UTC)[reply]