List of adverse effects of lurasidone

This is a list of adverse effects of the antipsychotic drug lurasidone, sorted by frequency of occurrence.

Very common

Very common (>10% incidence) adverse effects include:

• Somnolence^† (produces an intermediate degree of sedation compared to other atypical antipsychotics)
• Akathisia^†
• Fasting glucose increased^†
• Nausea^†
• Parkinsonism^†
• Insomnia^†

^† These are dose-dependent.

Common

Common (1–10% incidence) adverse effects include:

• Vomiting^†
• Dyspepsia^†
• Agitation^†
• Anxiety^†
• Dystonia
• Dizziness^†
• Fatigue
• Back pain^†
• Restlessness
• Hypersalivation^†
• Weight gain^†

^† These are dose-dependent.

Uncommon

Uncommon (0.1–1% incidence) adverse effects include:

• Orthostatic hypotension
• Syncope
• Stroke
• Seizure
• Suicidal ideation
• Elevated serum creatinine

Rare

Rare (<0.01% incidence) adverse effects include:

• Agranulocytosis
• Leukopaenia
• Neutropaenia
• Tardive dyskinesia
• Neuroleptic malignant syndrome

Unknown frequency

Unknown frequency adverse effects include:

• Transient ischaemic attack
• Hyperprolactinaemia (seems to be a rather prominent adverse effect according to a meta-analysis)
• Hypothermia