Celine Marmion
Celine J. Marmion | |
|---|---|
| Alma mater | University of Surrey (PhD) Kingston University (PGCE) |
| Scientific career | |
| Institutions | St Mary's University, Twickenham Royal College of Surgeons in Ireland |
Celine J. Marmion is a Professor of Chemistry at the Royal College of Surgeons in Ireland and President of the Institute of Chemistry of Ireland. She is a Fellow of the Royal Society of Chemistry and the Institute of Chemistry of Ireland. Marmion is involved with the design of new chemotherapeutic drugs.
Early life and education[edit]
Marmion earned her doctoral degree at the University of Surrey in 1994.[1] Her PhD research involved investigations into vanadium complexes and nitrogen fixation. In 1994 Marmion was appointed as a lecturer at St Mary's University, Twickenham, where she worked until 1995.[2] She returned to study in 1995, and earned a Postgraduate Certificate in Education (PGCE) at Kingston University.[3]
Research and career[edit]
In 1997 Marmion joined Royal College of Surgeons in Ireland as a lecturer in the Department of Chemistry.[2] She was promoted to Associate Professor in 2013 and Professor in 2018. Her research considers the design of metal-based chemotherapeutic drugs. In particular, this has included the design of targeted PtIV prodrugs.[4][5] Immunodeficient cancer patients are at risk of developing infections, which occasionally require antimicrobial prophylaxis. To better serve these patients Marmion developed a family of metallo-antibiotics, based on a Cu-N,N-framework, which can bind to DNA, has DNA oxidant properties and has antiproliferative and antimicrobial properties.[6] Her research has been supported by the Science Foundation Ireland (SFI) to create a prodrug strategy for multi-modal chemotherapeutics.[7]
Awards and honours[edit]
Her awards and honours include:
- 2009 Royal College of Surgeons in Ireland President's Teaching Award 'for excellence in teaching'[8]
- 2010 Vice-Dean of the Royal College of Surgeons in Ireland Faculty of Medicine & Health Sciences[8]
- 2013 President of the Irish Biological Inorganic Chemistry Society
- 2013 Elected Fellow of the Royal Society of Chemistry[4]
- 2015 Elected Fellow of the Institute of Chemistry of Ireland[3]
- 2015 Royal College of Surgeons in Ireland President's Teaching Award 'for excellence in teaching'[8]
- 2016 Royal College of Surgeons in Ireland Dean's Academic Award for 'Endeavour, Innovation, Collaboration and Service'[9]
- 2017 Irish Network of Healthcare Educators Education Research Grant[10]
- 2017 Vice President of the Institute of Chemistry of Ireland[11]
- 2019 President of the Institute of Chemistry of Ireland[12]
Selected publications[edit]
Her publications include:
- Marmion, Celine (2019). Metal-based Anticancer Agents. Royal Society of Chemistry. ISBN 9781788014069.
- Marmion, Celine J. (2004). "Hydroxamic Acids− An Intriguing Family of Enzyme Inhibitors and Biomedical Ligands". European Journal of Inorganic Chemistry. 2004 (15): 3003–3016. doi:10.1002/ejic.200400221.
- Marmion, Celine J. (2000). "Hydroxamic acids are nitric oxide donors. Facile formation of ruthenium(II)-nitrosyls and NO-mediated activation of guanylate cyclase by hydroxamic acids". Chemical Communications (13): 1153–1154. doi:10.1039/B001631O.
References[edit]
- ^ Dublin, T. U. "TU Dublin News". www.dit.ie. Retrieved 13 January 2020.
- ^ a b "Dr Celine Marmion – Biography". www.ucd.ie. Retrieved 13 January 2020.
- ^ a b "Profile". www.rcsi.com. Retrieved 13 January 2020.
- ^ a b Kenny, Reece G.; Chuah, Su Wen; Crawford, Alanna; Marmion, Celine J. (2017). "Platinum(IV) Prodrugs – A Step Closer to Ehrlich's Vision?". European Journal of Inorganic Chemistry. 2017 (12): 1596–1612. doi:10.1002/ejic.201601278. ISSN 1099-0682.
- ^ Kenny, Reece G.; Marmion, Celine J. (23 January 2019). "Toward Multi-Targeted Platinum and Ruthenium Drugs—A New Paradigm in Cancer Drug Treatment Regimens?". Chemical Reviews. 119 (2): 1058–1137. doi:10.1021/acs.chemrev.8b00271. ISSN 0009-2665. PMID 30640441. S2CID 58630540.
- ^ Ude, Ziga; Kavanagh, Kevin; Twamley, Brendan; Pour, Milan; Gathergood, Nicholas; Kellett, Andrew; Marmion, Celine J. (18 June 2019). "A new class of prophylactic metallo-antibiotic possessing potent anti-cancer and anti-microbial properties" (PDF). Dalton Transactions. 48 (24): 8578–8593. doi:10.1039/C9DT00250B. ISSN 1477-9234. PMID 30946409. S2CID 92997127.
- ^ Harrington, James (30 October 2018). "€3.5m investment in research commercialisation unveiled". Engineers Journal. Retrieved 13 January 2020.
- ^ a b c "Speakers – Celebrating Research – Past, Present, Future – Royal College Surgeons in Ireland". rcsi.ie. Retrieved 13 January 2020.
- ^ "RCSI Dean's Academic Award". www.rcsi.ie. Retrieved 13 January 2020.
- ^ inmedlogin. "Past Recipients". Irish Network of Healthcare Educators. Retrieved 13 January 2020.
- ^ "Annual General Meeting 2017 | Photo gallery | Institute of Chemistry of Ireland". www.chemistryireland.org. Retrieved 13 January 2020.
- ^ "Meet…". EuChemS Newsletters. 6 November 2019. Retrieved 13 January 2020.
| Authority control databases: Academics |
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