File:Glutamate-gated chloride channel receptor with bound ivermectin 3RHW.png
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Summary
| Description |
Top-down and side views of the C. elegans glutamate-gated chloride channel receptor (GluClR), a pentameric ligand-gated ion channel, bound to ivermectin. Ivermectin (royal blue) interacts with a binding pocket formed by the transmembrane domains of adjacent GluClR subunits (pale blue), "locking" the receptor in an activated (open) conformation that allows unrestricted passage of chloride (Cl−) ions into the cell. Created using QuteMol and GIMP. |
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| Date | |||
| Source | Own work, after PDB 3RHW. | ||
| Author | Fvasconcellos (talk · contribs) | ||
| Permission (Reusing this file) |
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File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 17:49, 29 November 2020 | | 1,200 × 2,470 (2.32 MB) | Fvasconcellos | {{Information |Description=Top-down and side views of the ''C. elegans'' glutamate-gated chloride channel receptor (GluClR), a pentameric ligand-gated ion channel, bound to {{w|ivermectin}}. Ivermectin (royal blue) interacts with a binding pocket formed by the transmembrane domains of adjacent GluClR subunits (pale blue), "locking" the receptor in an activated (open) conformation that allows unrestricted passage of chloride (Cl<sup>−</sup>) ions into the cell. C... |
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